home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
Shareware Overload Trio 2
/
Shareware Overload Trio Volume 2 (Chestnut CD-ROM).ISO
/
dir26
/
med9406b.zip
/
M9460183.TXT
< prev
next >
Wrap
Text File
|
1994-06-12
|
3KB
|
42 lines
Document 0183
DOCN M9460183
TI Thrombotic microangiopathy and retroviral infections: a 13-year
experience.
DT 9408
AU Ucar A; Fernandez HF; Byrnes JJ; Lian EC; Harrington WJ Jr; Department
of Medicine, University of Miami, School of Medicine,; FL 33136.
SO Am J Hematol. 1994 Apr;45(4):304-9. Unique Identifier : AIDSLINE
MED/94234121
AB Eleven of fifty serum samples collected from patients with a diagnosis
of thrombotic microangiopathy (TMA), from 1979 to 1991, tested positive
for antiretroviral antibodies. Seven had human immunodeficiency virus
(HIV) infection, and four had human lymphotrophic virus, type I (HTLV-I)
infection. All patients were treated with plasma exchange and/or
infusion, but only two of the HIV-infected patients obtained a complete
response (CR) and one of them died after a few months. Combined results
from the literature indicate that most patients with HIV infection
survive less than one year from the initial diagnosis of TMA. In the
setting of HIV infection, TMA is a treatable condition, but survival for
most patients is less than 12 months. Three of the four HTLV-I infected
patients with TMA had a CR. These observations strongly suggest that
both HIV and HTLV-I infections are associated with TMA, but rigorous
epidemiologic studies will be needed to determine the relative risk for
each. Retroviral infections should be considered in patients with TMA,
especially if the patient has associated risk factors and demographic
characteristics.
DE Adult AIDS-Related Opportunistic Infections/BLOOD/EPIDEMIOLOGY Case
Report DNA, Viral/ANALYSIS/GENETICS Female Hemolytic-Uremic
Syndrome/BLOOD/*COMPLICATIONS/EPIDEMIOLOGY Human
HIV/GENETICS/IMMUNOLOGY HIV Antibodies/ANALYSIS/IMMUNOLOGY HIV
Infections/BLOOD/COMPLICATIONS/EPIDEMIOLOGY HTLV
Antibodies/ANALYSIS/IMMUNOLOGY HTLV-I/GENETICS/IMMUNOLOGY HTLV-I
Infections/BLOOD/COMPLICATIONS/EPIDEMIOLOGY Male Middle Age
Polymerase Chain Reaction Purpura, Thrombotic
Thrombocytopenic/BLOOD/*COMPLICATIONS/ EPIDEMIOLOGY Retroviridae
Infections/BLOOD/*COMPLICATIONS/EPIDEMIOLOGY Risk Factors Survival
Analysis Time Factors JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).